The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
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Previously funded studies appear chronologically, with the most recent appearing first.
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Therapeutic Pipeline Program, 2019Clinical Development of AKST4290 as a Novel Parkinson’s Therapeutic
Study Rationale:
There is clear evidence that the immune system plays an important role in the development and progression of Parkinson's disease. Novel therapies targeting the recruitment of immune... -
Research Grant, 2019Restoring the Nigrostriatal Pathway with Living Micto-tissue Engineered Axonal Tracts Supplement
Promising Outcomes of Original Grant:
The classic motor deficits of Parkinson’s disease (PD) are caused by degeneration of dopamine neurons, resulting in the loss of part of the neurons called axonal... -
Research Grant, 2019Longitudinal Examination of Problems that Bother People with Parkinson’s
Study Rationale:
Using the Fox Insight research platform, we extracted and analyzed reports in patients’ own words about what problems bother them and how these problems affect their daily functioning... -
Research Grant, 2019Validation of Microglial CRAC Channels as a Therapeutic Target for Parkinson’s Disease
Study Rationale:
Inflammation of the central nervous system mediated by microglial cells is a major feature of Parkinson’s disease. Vivreon Biosciences is developing Parkinson’s disease therapeutics... -
Astrocyte Biology in Parkinson's Disease, 2019Control of Astrocyte Function by LRRK2
Study Rationale:
Mutations in the LRRK2 gene are known to cause Parkinson’s disease (PD), but how mutations in this gene lead to neuron death is not yet known. Astrocytes, which are brain cells that s... -
Astrocyte Biology in Parkinson's Disease, 2019How Astrocytes Cause Neuronal Loss by Reacting to Alpha-synuclein
Study Rationale:
Research in Parkinson’s disease has largely focused on events that occur within neurons that are lost in disease. However far more abundant than neurons in the human brain are a type...
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Our funding programs support basic, translational and clinical research from academia and industry.