The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
Search or browse funded studies
Previously funded studies appear chronologically, with the most recent appearing first.
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Biomarkers, 2005Epigenetic Regulation of the alpha-synuclein Gene as a Biomarker of Susceptibility to PD
Available genetic information in Parkinson's disease does not account for all phenomena in the clinical expressivity of the disease. For example, in the Contursi kindred with the A53T substitution in...
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Biomarkers, 2005Biomarkers in Human Cerebrospinal Fluid
This proposal involves confirmatory as well as discovery-type proteomic analyses of protein profiles in the human cerebral spinal fluid (CSF) obtained from patients with Parkinson's disease (PD) at...
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Community Fast Track, 2005Nigrostriatal Dopaminergic Degeneration and Alpha-synuclein Aggregation in Mice with Reduced TrkB Signaling
Parkinson's disease (PD) is characterized by progressive loss of dopaminergic neurons and deposition of cytoplasmic protein aggregates termed Lewy bodies (LB) in a brain structure termed substantia...
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Community Fast Track, 2005Pathophysiological Role of PINK1 in Rodent Brain
Mutations in the PINK1 gene were recently linked to autosomal recessive parkinsonism. However, to date, very little is known about the role of PINK1 in the brain. Our group has ample expertise with...
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Community Fast Track, 2005Novel Therapeutic Approaches for Parkinson ’s Disease
Our goal is to develop novel therapeutic agents for the treatment of Parkinson's disease. We will focus on two compounds. One of these blocks the mitochondrial permeability transition (MPT), which is...
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Community Fast Track, 2005Neoangiogenesis and Blood-Brain Barrier in L-DOPA-induced Dyskinesia
Fluctuations in brain levels of levodopa play a key role in the production of dyskinesia (abnormal involuntary movements) and motor fluctuations in Parkinson's disease. This project explores the...
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Our funding programs support basic, translational and clinical research from academia and industry.