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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • Cell Line, 2002
    Development and Utilization of Dopaminergic Cell Lines for the Treatment of Parkinson's Disease

    We have recently succeeded in differentiating adult human and animal bone marrow stromal stem cells (BMSCs) into neurons (nerve cells). A subpopulation of the neurons activates functions that are...

  • Cell Line, 2002
    Development & characterization of adult substantia nigra derived neural progenitor cells

    There is growing evidence that certain areas of the adult central nervous system retain the capacity to generate new neurons from endogenous immature progenitor cells. Our preliminary results show...

  • Cell Line, 2002
    Establishing stable lines of human nigral dopaminergic progenitor cells

    We intend to develop lines of clonal, stable and self-renewing human dopamine-producing neuronal progenitor cells. These will be derived from the part of the midbrain that gives rise to dopamine...

  • Cell Line, 2002
    Dopamine Neurons Derived from Human ES Cells

    Embryonic stem (ES) cells proliferate extensively, and preliminary data show that animal ES cells can be manipulated to generate highly enriched populations of dopamine neurons that express genes...

  • Cell Line, 2002
    Unlimited Numbers of Purified Midbrain Dopamine Neurons from Human Embryonic Stem Cells

    The fact that dopamine (DA) cells are lost specifically but other nerve cells are still intact makes Parkinson's disease (PD) uniquely amenable to cell replacement therapy. Early attempts have...

  • Cell Line, 2002
    Banking of and Dopamine Neuronal Production from Human Neural Stem Cells

    Transplantation of dopamine neurons in Parkinson's disease has resulted in significant improvements for some patients. However, large-scale clinical trials are impossible due to the technical and...

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