The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
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Previously funded studies appear chronologically, with the most recent appearing first.
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Community Fast Track, 2003Multi-single Unit Electrophysiological Characterization of Dyskinesia Induced by Dopamimetic Drugs
Parkinsonian patients develop debilitating motor complications caused by the best treatments of the disease, the levodopa and the dopamine agonists. Among other phenomena, it is known that these...
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Community Fast Track, 2003Reconstructing the neural circuits in Parkinson’s, using biodegradablepolymer bridges or striatal co-grafts to encourage neural outgrowth from transplantedtissue
In Parkinson's disease, the neurocircuitry, called the nigrostriatal pathway, is lost. This pathway links the substantia nigra to the striatum. In neural tissue transplants for Parkinson's disease...
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Community Fast Track, 2003Effects of Subthalamic Nucleus Stimulation on Sensorimotor Integration
In addition to the well-known motor symptoms, sensory symptoms are also common and sensory abnormalities have been documented in Parkinson's disease (PD). Although deep brain stimulation (DBS) of the...
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Community Fast Track, 2003The regulation of synaptic dopamine by striatal nicotinic receptors
A new category of drugs that offer a promising therapy for Parkinson's disease are drugs that act at a key subtype of brain receptors for the neurotransmitter acetylcholine, the nicotine-sensitive...
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Community Fast Track, 2003Intracellular Trafficking Dysfunction Caused by Alpha-synuclein Aggregation
A growing body of evidence suggests that aggregation of a neuronal protein named a-synuclein might be the fundamental cause of many neurodegenerative diseases, such as Parkinson's disease (PD)...
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Community Fast Track, 2003Analysis of genetic factors influencing alpha-synuclein toxicity
Parkinson's disease is a devastating disease that robs its victims of the ability to direct and control normal movement. These symptoms result from the death of a particular class of nerve cell in the...
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Our funding programs support basic, translational and clinical research from academia and industry.