The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
Search or browse funded studies
Previously funded studies appear chronologically, with the most recent appearing first.
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Improved Biomarkers and Clinical Outcome Measures, 2019Correlating MRI, Pathology and Cognitive Assessments toward Biomarkers of Cognitive Decline
Study Rationale:
Parkinson’s studies are working to identify magnetic resonance imaging (MRI) biomarkers for early diagnosis, disease severity and progression. However, attempts to explore how brain... -
Target Validation, 2010Treating Early Cognitive Impairments and Associated Movement Control Deficits by Stimulating alpha4beta2* nAChRs
Objective/Rationale:
Cholinergic systems decline early in PD and are hypothesized to contribute to cognitive impairments as well as to impairments in performing complex movements and postural... -
Cognitive Deficits and Mood Disorders in Parkinson's Disease, 2008Validation of the Dopamine-depleted CHT Hemizygous Pre-Clinical Model as an Animal Model of Parkinson's Disease with Dementia
Objective/Rationale:
Parkinson’s disease is traditionally thought of as a motor disorder. However, in addition to problems with movements, patients frequently develop cognitive problems leading to... -
Critical Challenges in PD: Postural Instability and Gait Dis, 2012Targeted Cognitive Training Program for Freezing of Gait
Promising Outcomes of Original Grant:
In our original study we investigated the processes underlying the freezing phenomenon in PD. In this work we found symptoms of freezing of gait (FOG) could be... -
Therapeutic Pipeline Program, 2016Cognitive Behavioral Therapy for Anxiety Disorders in Parkinson's Disease
Study Rationale:
Anxiety disorders occur in up to 35 percent of people with Parkinson's disease and can have a negative impact on gait, involuntary movements, motor fluctuations and quality of life... -
Research Grant, 2016Inhibition of Striatal-enriched Phosphate (STEP) to Improve Parkinson-related Cognitive Dysfunction
Promising Outcomes of Original Grant:
Our original funded project was designed to examine absorption and distribution of the STEP (Striatal-Enriched Phosphatase), a protein associated with several...
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Our funding programs support basic, translational and clinical research from academia and industry.