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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • Cognition Biomarkers, 2013
    Assessment of Plasma Glucosylceramides and Ceramides as Biomarkers of Cognitive Impairment in Parkinson's Disease

    Objective/Rationale:
    Metabolism of the lipids glucosylceramide and ceramide is altered in Parkinson’s disease (PD). GBA mutations in this pathway, causing a build-up of glucosylceramide, increase the...

  • Defining Cognitive Phenotypes of Parkinson’s Disease, 2011
    The Relationship Between Cognitive Phenotypes of PD with Visual Hallucinations and 5HT2A Receptors in the Inferotemporal Cortex

    Objective/Rationale:
    The project aims to understand the mechanisms underlying cognitive deficits that are associated with visual hallucinations (VH) in Parkinson’s disease (PD). We have previously...

  • MJFF Research Grant, 2009
    Clinicogenetic Studies of LRRK2 G2019S in Tunisia

    Objective/Rationale:
    Parkinson’s disease (PD) is a prevalent, heterogeneous disorder with a complex, multifactorial etiology. In Tunisia, North Africa, the burden of genetically-defined LRRK2 G2019S...

  • PD Subtypes, 2007
    Evaluating Novel Predictors of Parkinson's Disease Progression

    How the symptoms of Parkinson’s disease progress varies from patient to patient, and it is hard to predict which patients will progress more quickly than others. One way to figure this out is to look...

  • MJFF Research Grant, 2011
    Assessing and Diagnosing Anxiety in Patients with Parkinson's Disease

    Promising Outcomes of Original Grant:
    A previous MJFF sponsored study showed that the available anxiety questionnaires are not suitable to assess anxiety in Parkinson’s disease (PD). The different...

  • Rapid Response Innovation Awards, 2013
    Evaluation of Targeted Plasticity Therapy as a Treatment for Motor Dysfunction in Parkinson’s Disease

    Objective/Rationale:             

    Deterioration of motor function is a debilitating symptom of Parkinson’s disease (PD). We have recently developed a novel method that utilizes stimulation of the...

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