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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • Research Grant, 2016
    Characterization, Optimization and Validation of a Preformed Fibril Pre-clinical Model of Parkinson's Disease

    Study Rationale:
    New pre-clinical models have been developed to study the hypothesis that damaging forms of alpha-synuclein (protein involved in Parkinson's) spread across brain regions from a single...

  • Research Grant, 2016
    Design and Identification of a LRRK2 Kinase Structural Surrogate

    Study Rationale:

    Due to the importance of the LRRK2 protein in Parkinson's disease (PD), many academic and industrial laboratories have attempted to solve the three-dimensional structure of the kinase...

  • Research Grant, 2017
    Using Neural Cells to Test New Drugs that Activate PINK1 and Parkin

    Promising Outcomes of Original Grant:
    Even though most people with Parkinson's disease (PD) do not have a genetic mutation -- a change in their DNA -- that causes the disease, genes can influence the...

  • Access to Data and Biospecimens, 2018
    Uric Acid as an Antioxidant Treatment for LRRK2-associated Inherited Parkinson's Disease

    Objective/Rationale:
    Uric acid is a chemical produced naturally in the human body. In this project, we aim to investigate whether uric acid is an antioxidant capable of reducing the risk of Parkinson's...

  • Research Grant, 2018
    Does Mitochondrial Dysfunction in the Skin Predict That in the Brain?

    Study Rationale:
    Mitochondria -- the power generators of the cell -- do not function properly in Parkinson's disease (PD). This dysfunction, however, is not always present and can vary in its severity...

  • Biomarkers Across Neurodegenerative Diseases, 2018
    Brain Networks as Targets of Neurodegeneration in Parkinson's and Alzheimer's Diseases

    Study Rationale:
    This study builds on two recent discoveries in neuroscience: first, the brain is organized in large-scale networks of nerve cells; and second, the clumps of alpha-synuclein, amyloid...

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Our funding programs support basic, translational and clinical research from academia and industry.

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