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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • Diversity, Equity and Inclusivity in Parkinson's research, 2021
    Study of Cognitive Differences in a South Asian Population with Parkinson’s Disease

    Study Rationale: Research on Parkinson’s disease (PD) has focused mainly on White, affluent populations. Little is known about PD in people of color. East London is one of the most diverse parts of...

  • , 2021
    Evaluating Patient-reported Outcome Assessment in Early Parkinson’s Disease

    Study Rationale: There are currently no validated tools for assessing functional changes in people at the earliest clinical stages of Parkinson’s disease (PD). Available approaches lack sufficient...

  • Research Grant, 2021
    Exploring the Protective Effect of Modulating Brain Cells’ Electrical Activity in Parkinson’s Disease

    Study Rationale: The symptoms of Parkinson’s disease (PD) arise when more than 70% of the dopamine-producing neurons in the brain region regulating movement are lost. This disruption increases the...

  • Fall 2021 RFP: Expanding Biological Understanding of PD, 2021
    Using Human iPSC to Explore the Role of the STING Pathway in Parkinson's Disease

    Study Rationale: Inflammation is recognized as a factor in the progression of Parkinson’s disease (PD). The PD-associated genes PINK1 and Parkin are involved in eliminating damaged cell components...

  • Fall 2021 RFP: Expanding Biological Understanding of PD, 2021
    Characterizing the Impact of a Protective LRRK2 Variant on Biochemical and Cellular Function

    Study Rationale: The LRRK2 gene is one of the most important genes involved in increasing the risk of Parkinson’s disease (PD). Changes in the gene, called mutations, can cause people to develop PD –...

  • Fall 2021 RFP: Accelerating Early Proof-of-Concept Testing of Promising PD Therapies, 2021
    Preclinical Development of Immune-inhibiting Small Molecules as Therapeutics for Parkinson’s Disease

    Study Rationale: Brain inflammation plays an important role in the pathology of Parkinson’s disease (PD). One of the key proteins involved in this inflammatory process is STING (stimulator of...

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