The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
Search or browse funded studies
Previously funded studies appear chronologically, with the most recent appearing first.
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Accelerating Biological Understanding and Therapeutic Translation for Parkinson’s Disease Program, 2023Examining a Novel GCase Activator in Neurons Derived from People with Parkinson’s Disease
Study Rationale: Decreased function of the lysosomal enzyme GCase is associated with Parkinson’s disease (PD). We discovered that LIMP-2, the protein that transports GCase to the lysosome, also...
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Research Grant, 2023(SUPPLEMENT) The Foundational Data Initiative
Study Rationale: This project aims to produce foundational data that will provide a resource for understanding the molecular basis of Parkinson’s disease (PD). The work, conducted in cells collected...
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Lysosomal Biomarkers Program, 2023Developing a Targeted Proteomic Test to Monitor Blood Samples for Lysosomal Signatures of Parkinson’s Disease
Study Rationale: Lysosomes are structures that help clear cells of molecular debris, and lysosomal dysfunction has been linked to neurodegeneration in Parkinson’s disease (PD). In this study, we will...
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Lysosomal Biomarkers Program, 2023Measurement of Neuronal Extracellular Vesicles as a Blood-based Biomarker for Lysosomal Function
Study Rationale: Parkinson’s disease (PD) is associated with the aggregation of toxic proteins, a buildup due partly to the reduced ability of lysosomes to degrade these proteins. Improving lysosome...
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Research Grant, 2023(SUPPLEMENT) Development of an Imaging Tracer for Measuring Alpha-synuclein
Study Rationale: The discovery of new treatments for Parkinson’s disease (PD) has been hampered by the amount of time it can take (typically a number of years) to determine whether a drug works in a...
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Research Grant, 2023Development of a Protein Biomarker Panel to Measure Parkinson’s Disease Heterogeneity and Progression
Study Rationale: According to The Michael J. Fox Foundation, the need for biomarkers that provide an objective assessment for Parkinson’s disease (PD) “has become more urgent as more projects enter...
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Our funding programs support basic, translational and clinical research from academia and industry.