The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
Search or browse funded studies
Previously funded studies appear chronologically, with the most recent appearing first.
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Repositioning Drugs for PD, 2014DPP-4 Inhibitors for the Treatment of Parkinson’s Disease (Supplement)
Promising Outcomes of Original Grant:
Dipeptidyl protease-4 (DPP-4) inhibitors are widely used in the effective treatment of type 2 diabetes to safely regulate blood glucose levels. DPP-4 is the key... -
Research Grant, 2014Chemical Modulator of Chaperone-mediated Autophagy in Parkinson's Disease
Objective/Rationale:
Brain cells depend on very efficient surveillance systems to identify defective components and break them apart to avoid accumulation and toxicity. We have found that in the brain... -
Rapid Response Innovation Awards, 2014Impact of the Medical Food ErgoD2® on Alpha-synuclein and Iron Levels
Objective/Rationale:
Although the causes of Parkinson’s disease (PD) are yet unknown, the overall health of the body likely plays a major role in disease initiation and progression... -
Therapeutic Pipeline Program, 2014Evaluating the Safety, Tolerability and Efficacy of SYN120 in Parkinson’s Disease Dementia
Study Rationale:
Cognitive impairments — common in Parkinson’s disease — are associated with an imbalance in neurotransmitters (substances that allow nerve cells to communicate with one another) such... -
Research Grant, 2014Efficacy and Safety of APL-130277 in People with Parkinson’s Disease who are Apomorphine Naïve
Study Rationale:
Apomorphine is a drug that is used to control “off” episodes in people with Parkinson’s disease. At present, the drug is given by injection under the skin and starts... -
Therapeutic Pipeline Program, 2014Effects on Gait and Balance of Augmenting Cholinergic Function
Study Rationale:
Impairments of gait and balance are common and life-altering in patients with Parkinson’s disease (PD). These impairments are incompletely controlled with...
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Our funding programs support basic, translational and clinical research from academia and industry.