The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
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Previously funded studies appear chronologically, with the most recent appearing first.
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Research Grant, 2021Parkinson’s Disease Patient Report of Problems (PD-PROP) Curation
Study Rationale:
What people with Parkinson’s feel and experience about their disease, and how it affects their lives, is of paramount importance to their care and participation in research. The... -
Priority Biology, 2021Studying the Properties of Alpha-Synuclein Aggregates Amplified from Human Cerebrospinal Fluid
Study Rationale:
Aggregates of the protein alpha-synuclein, which accumulate in the brains of people with Parkinson’s disease (PD), can also be detected in biofluids like cerebrospinal fluid (CSF)... -
Research Grant, 2021Hypoxia (Limiting Oxygen Levels) as a Novel Treatment for Parkinson’s Disease
Study Rationale:
Many anecdotes suggest that people with Parkinson’s disease (PD) can experience a marked improvement in symptoms when they travel to the mountains or during flights at high altitude... -
Biosample Use Program, 2021Evaluating Neurotoxic Metabolites as Biomarkers of Parkinson’s Progression
Study Rationale:
Individuals with Parkinson’s disease (PD) show elevated markers of inflammation in their brains, cerebrospinal fluid and blood. We think that inflammation drives the worsening of... -
Target Advancement Program, 2021SCARB2 as a Potential Target in Parkinson’s Disease
Study Rationale:
Mutations in GBA, a gene that encodes an enzyme called glucocerebrosidase, are a common risk factor for Parkinson’s disease (PD). Inside cells, glucocerebrosidase must be escorted to... -
Target Advancement Program, 2021Targeting the Chemical Modification of DNA to Suppress Neurodegeneration in Parkinson’s Disease
Study Rationale:
Genes can be switched on or off by proteins that add and remove chemical modifications to DNA. We and others have shown that the chemical modification of genes important for...
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Our funding programs support basic, translational and clinical research from academia and industry.