The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
Search or browse funded studies
Previously funded studies appear chronologically, with the most recent appearing first.
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Community Fast Track, 2004Characterization of DJ-1 Null Transgenic Mice
The protein DJ-1 has been implicated to play a role in neurodegenerative diseases, such as multiple system atrophy and Parkinson's disease (PD). Mutations in the DJ-1 gene have been linked to an...
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Community Fast Track, 2004The role of nociceptin/orphanin FQ in regulation of motor behavior and induction of parkinsonism
Nociceptin/orphanin FQ (N/OFQ) is an opioid-like neuropeptide discovered in the mid 90's, which activates a G-protein coupled receptor, the NOP receptor. N/OFQ and its receptor are diffusely expressed...
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Community Fast Track, 2004Engrailed as a Potential Therapeutic Target in Parkinson's Disease
Transcription factors constitute a class of molecules that regulate gene expression. Homeoproteins Engrailed-1 and Engrailed-2 (collectively Engrailed) are transcription factors expressed in the...
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Community Fast Track, 2004Neuregulin-2â: A Novel Trophic Factor for Midbrain Dopamine Neurons
The continuing search for new and effective trophic factors as candidate therapeutics for treatment of Parkinson's disease is of great importance. This project will evaluate two proteins from the...
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Community Fast Track, 2004DJ-1 Function in Dopaminergic Neuronal Function and Survival
Parkinson's disease is the second most common neurodegenerative disease affecting the elderly. The movement disorder is caused by progressive loss of dopamine producing neurons. Loss of function...
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Community Fast Track, 2004Gene Transfer of Pleiotrophin to Aged Parkinsonian Pre-Clinical Models
Parkinson's disease involves the death of a specific population of neurons in the brain that supply the neurotransmitter dopamine (DA). A group of molecules termed neurotrophic factors have been...
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Our funding programs support basic, translational and clinical research from academia and industry.