The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
Search or browse funded studies
Previously funded studies appear chronologically, with the most recent appearing first.
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MJFF Research Grant, 2011In Vivo Validation of the AAV-alpha-synuclein Vectors Generated by UNC for Distribution to MJFF Supported Research Community
Objective/Rationale:
The Michael J. Fox Foundation would like to generate those tools and reagents that can be of greatest use to PD researchers. Working with Dr. R. Jude Samulski at The University... -
MJFF Research Grant, 2011Nmnat Function in Axonal Neuroprotection
Promising Outcomes of Original Grant:
In the previous application, we tested the hypothesis that gene delivery of NMNAT-1 would protect striatal innervation in 6-OHDA lesioned pre-clinical models and... -
Repositioning Drugs for PD, 2011Droxidopa Treatment for Cognitive Impairment in Parkinson's Disease
Objective/Rationale:
Memory, concentration, and other cognitive operations are sometimes impaired in Parkinson's disease (PD), but available treatment options are very limited. This project will test... -
Rapid Response Innovation Awards, 2011Pathogenic Significance of the Hyperpolarization-activated Current (Ih) in the Degeneration of Dopaminergic Neurons
Objective/Rationale:
The neurotoxin MPTP is believed to kill nigral dopaminergic neurons by inhibiting mitochondrial metabolism, thus producing Parkinson’s signs in pre-clinical models. Recent studies... -
MJFF Research Grant, 2011GeneGo LRRK2 Pathway Map - Laura Brovold (GeneGo/Thomson Reuters)
Objective/Rationale:
Human diseases are inherently complex and involve a multitude of interconnected proteins, which function in groups defined as pathways and complexes. In order to understand... -
Dyskinesia, 2011Role of Gad1 in l-DOPA-induced dyskinesias
Objective/Rationale:
Levodopa remains the most efficient agent used for the Symptoms & Side Effects treatment of Parkinson’s disease. Unfortunately, levodopa administration for several years also...
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Our funding programs support basic, translational and clinical research from academia and industry.