The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
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Previously funded studies appear chronologically, with the most recent appearing first.
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Biomarkers to Support Therapeutic Trials Program, 2023Using the Chemical Modification of Alpha-synuclein to Define Disease State and Facilitate Patient Stratification in Parkinson’s Disease
Study Rationale: Novel disease-modifying treatments for Parkinson’s disease (PD) are urgently needed as the prevalence of the disease is increasing and no cure is available. At this point, we have...
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Accelerating Biological Understanding and Therapeutic Translation for Parkinson’s Disease Program, 2023Targeting the Dopamine D1 Receptor for a Treatment of Parkinson’s Disease with Minimal L-DOPA-induced Dyskinesia
Study Rationale: L-DOPA is the primary drug used for treating the mobility loss that occurs in Parkinson’s disease (PD) due to decreases in dopamine. Although L-DOPA enhances mobility, chronic...
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Research Grant, 2023Evaluation of a Digital Therapeutics (DTx) Mobile App and Algorithm for Personalized Medication and Treatment Plan Optimization for People with Parkinson’s Disease
Study Rationale: People with Parkinson’s disease (PD) have few options for keeping their symptoms under control. An app that could automatically monitor PD symptoms, like tremors, could allow users to...
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Biomarkers to Support Therapeutic Trials Program, 2023Using Neurophysiology as a Stratification Tool for Synucleinopathy
Study Rationale: Although numerous disease-modifying drugs are being developed for Parkinson’s disease (PD), the current methods used to identify people suitable for clinical trials are costly...
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Research Grant, 2023Understand Me for Life: Using Noise-augmented Automatic Speech Recognition to Improve Intelligibility in Parkinson’s Disease
Study Rationale: Most people with Parkinson’s disease (PD) develop voice and speech problems at some point during the course of the disease. Such problems, collectively known as the motor speech...
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Translational Pipeline Program, 2023Inhibiting Faulty DNA Repair as a Strategy for Preventing Neuronal Loss in Parkinson’s Disease
Study Rationale: Cells have mechanisms for repairing damaged DNA. Unfortunately, these repair mechanisms can themselves become inefficient and error-prone as we age — leading to the accumulation of...
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Our funding programs support basic, translational and clinical research from academia and industry.