The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
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Previously funded studies appear chronologically, with the most recent appearing first.
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Astrocyte Biology in Parkinson's Disease, 2019Characterization of Astrocytes in Aging and Lewy Body Pathology
Study Rationale:
Astrocytes are brain cells with crucial roles, including communication between nerve cells, clearance of unwanted material, and response to injury. It has been suggested that... -
Research Grant, 2019Long-acting GM-CSF Fusion Protein (PDM608) for the Treatment of Parkinson’s Disease
Study Rationale:
Emerging evidence suggests that the modulating the peripheral immune system can be a powerful disease-modifying approach for the treatment of Parkinson's disease (PD). We have... -
Access to Data and Biospecimens, 2020Association of Repetitive DNA Elements in Parkinson’s Disease Risk and Progression
Study Rationale:
Repetitive DNA elements such as “jumping genes” were previously considered ‘junk DNA’. However, it is now known that these elements are involved in the development of several diseases... -
Therapeutic Pipeline Program, 2020Anle138b Clinical Phase 1 Studies: Food Effect, Safety and Tolerability as well as Pharmacokinetics in Parkinson´s Disease Patients
Study Rationale:
Clumps of the protein alpha-synuclein, called Lewy bodies, are a hallmark of Parkinson’s disease and a promising target for therapeutic development. Anle138b is a drug-like compound... -
Alpha-Synuclein Imaging, 2020Optimization of Morphomer-Based Alpha-synuclein PET Tracers
Study Rationale:
The team at AC Immune has discovered a variety of compounds that can bind to a specific Parkinson’s disease-associated form of the protein alpha-synuclein. AC Immune has previously... -
Alpha-Synuclein Imaging, 2020PET Imaging Probe Development for Alpha-synuclein
Study Rationale:
Alpha-synuclein is a protein that can clump to form Lewy bodies and lewy neurites, which are a hallmark of Parkinson's disease. Being able to identify these clumps in living patients...
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Our funding programs support basic, translational and clinical research from academia and industry.