The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
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Previously funded studies appear chronologically, with the most recent appearing first.
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- Target Advancement Program, 2018The Role of Lysosomal Lipid Metabolism in Parkinson's Disease
Study Rationale:
Lysosomes -- tiny bubbles inside the cell responsible for disposing of its waste -- don't work as they should in brain cells of people with Parkinson's disease (PD). Lysosomes are... - Mitochondrial Biomarkers Program, 2018Mitochondrial DNA Damage in a Pesticide-exposed Cohort
Study Rationale:
Environmental poisons may cause or contribute to some cases of Parkinson’s disease (PD). Mitochondrial impairment is seen in all forms of PD. Some environmental exposures, such as... - Improved Biomarkers and Clinical Outcome Measures, 2018Cognitive-driven Activities of Daily Living Impairment as a Predictor for Parkinson's Disease Dementia
Study Rationale:
Mild cognitive impairment in Parkinson's disease (PD-MCI) is the highest risk factor for Parkinson's disease dementia (PDD). The core feature for differentiating PDD from PD-MCI is... - Therapeutic Pipeline Program, 2018The PERSPECTIVE study: Personalized Speech Therapy for Active Conversation
Study Rationale:
Many people with Parkinson's disease have speech problems, which can be overcome by instructing patients to intentionally speak louder. However, to use this technique in daily life... - Inflammation Biomarkers Program, 2018Studying Age-related Chronic Inflammation in Parkinson's Disease
Study Rationale:
Aging increases the risk of Parkinson's disease (PD), making the disease more likely to occur at an older age. It is unclear how biological changes that accompany normal aging are... - Inflammation Biomarkers Program, 2018Studying Abnormalities of Immune System Aging in Parkinson's Disease
Study Rationale:
While immune cells protect us from infection, they can also cause damage by inadvertently responding to other, non-infectious events. Such immune response occurs in Parkinson's disease...

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Our funding programs support basic, translational and clinical research from academia and industry.