The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
Search or browse funded studies
Previously funded studies appear chronologically, with the most recent appearing first.
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Research Grant, 2018Studying Structures of LRRK2 to Understand and Slow Parkinson's Disease
Study Rationale:
Mutations in the LRRK2 gene are a leading genetic cause of Parkinson's disease (PD) and cause dysfunction in the LRRK2 protein. We are studying the structures of normal and abnormal... -
Inflammation Biomarkers Program, 2018Influence of Inflammation on Symptoms and Progression of Parkinson's Disease
Study Rationale:
Symptoms of Parkinson's disease (PD) are different for different people, suggesting a strong influence of genetic and/or non-genetic factors, including inflammation. While many... -
Improved Biomarkers and Clinical Outcome Measures, 2018The Role of Circular RNAs in Parkinson's Disease and Dementia
Study Rationale:
Biomarkers are objectively measurable characteristics that can be used to diagnose a disease or to track its progression. In this study, we will explore circular RNAs -- a recently... -
Research Grant, 2018Inducing Aging in Brain Cells to Better Understand Parkinson's Disease
Study Rationale:
Age is the biggest risk factor for Parkinson's disease (PD), with disease incidence rising steeply among persons 60 or older. The reason for this remains unknown. Research suggests... -
Therapeutic Pipeline Program, 2018Developing a Blocker of Alpha-synuclein Production for the Treatment of Parkinson's Disease
Study Rationale:
Alpha-synuclein is a sticky protein that clumps in the brains of people with Parkinson's disease (PD). Duplication or triplication of SNCA, a gene responsible for the production of... -
LEAPS, 2018Studying LRRK2 Mutations as a Possible Cause of Waste Buildup in Nerve Cells
Study Rationale:
Health and longevity of brain cells depends on the efficiency of their waste removal process, known as autophagy or self-eating. Cells use autophagy to get rid of unwanted protein...
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Our funding programs support basic, translational and clinical research from academia and industry.