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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • Rapid Response Innovation Awards, 2010
    Selective Neuroprotective Effects of the S18Y Polymorphic Variant of UCH-L1

    Promising Outcomes of Original Grant:
    We were able to replicate in an in vivo setting in the nigrostriatal system our previous observation in neuronal cell cultures that lack of UCH-L1 did not alter...

  • Rapid Response Innovation Awards, 2010
    Dopamine D1-D3 Receptor Heteromer as a New Target for Parkinson's Disease

    Objective/Rationale:   
    Receptor heteromers must be understood as dimeric or higher order molecular entities that are the result of combinatorial evolution and that are endowed with unique...

  • Rapid Response Innovation Awards, 2010
    Screen for Novel Glucocerebrosidase-Interacting Parkinson's Genes

    Objective/Rationale:
    Our goal is to discover new genes that lead to Parkinson’s disease.  Most of the known causes of Parkinson’s disease are rare and account for a minority of patients. However, it...

  • Rapid Response Innovation Awards, 2010
    Nasal PD Treatment-Proof-of-Concept

    Objective/Rationale:

    • In animal models of PD, brain injections of certain neurotrophic factors prevent degeneration of midbrain dopaminergic neurons.
    • Clinical testing of brain injected gene vectors...
  • Rapid Response Innovation Awards, 2010
    Functional Genomic Screening to Identify Novel Regulators of Parkin

    Objective/Rationale:    
    In normal cells, Parkin protein senses damage of critical cellular organelles known as mitochondria and promotes recycling of their contents. Mitochondria are the energy...

  • MJFF Research Grant, 2010
    Role of H1N1 Influenza Virus in the Etiology of Parkinson's Disease

    Objective/Rationale:    
    Viruses (including influenza) have also been proposed to be an etiological agent for PD based on the appearance of otherwise non-explained clusters of parkinsonism. Recently...

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Our funding programs support basic, translational and clinical research from academia and industry.

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