The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
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Previously funded studies appear chronologically, with the most recent appearing first.
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MJFF Research Grant, 2009Validation of Dyskinesia Rating Scales
Objective/Rationale:
Dyskinesias, or involuntary jerking movements, are troublesome problems for many Parkinson’s disease patients. Chemical studies have led to the development of several new... -
Rapid Response Innovation Awards, 2009Plasma Biomarker Screen for Neurodegeneration and Signaling Proteins
Objective/Rationale:
The cells and tissues of the body can “communicate” with one another using small secreted proteins that can be found in the blood. There are several hundred of these cellular... -
Rapid Response Innovation Awards, 2009Oligomeric Equilibrium in Male and Female Brains with Alpha-synuclein Pathology
Objective/Rationale:
Men are more susceptible to Parkinson's disease than women. Alpha-synuclein aggregates are a hallmark of the disease and it is increasingly believed that alpha-synuclein... -
Rapid Response Innovation Awards, 2009Characterizing Transgenic Pre-Clinical Models that Express a Mutant LRRK2 Gene Selectively in Adulthood
Objective/Rationale:
Mutations of the gene LRRK2 are identified in both familial and sporadic Parkinson’s disease (PD). How mutation of the LRRK2 gene causes neuronal dysfunction in PD remains to be... -
Postural Instability and Gait Disturbances, 2009Role of the Posterior Parietal Cortex and Pedunculopontine Nucleus in the Pathophysiology of Freezing of Gait: An MRI and TMS Study
Objective/Rationale:
Although disturbances in the posterior parietal cortex (PPC) and pedunculopontine nucleus (PPN) are thought to be involved in the development of freezing of gait (FOG) in PD... -
Postural Instability and Gait Disturbances, 2009Neuroanatomical Correlates of Dopamine Responsive and Non-responsive Gait and Balance Impairment in Parkinson's Disease
Objective/Rationale:
Parkinson’s is more than a motor disorder that responds to dopamine replacement. Dopamine non-responsive features account for much of the disability that develops with disease...
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Our funding programs support basic, translational and clinical research from academia and industry.