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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • MRI Biomarkers Program, 2025
    Molecular MRI Correlates of Parkinsonian Neurodegeneration

    Study Rationale: New imaging tools for Parkinson’s disease (PD) are urgently needed to help accelerate the development of new treatments. A special type of MRI scan, CEST MRI, can detect changes in...

  • Neuronal Synuclein Disease Endotypes 2024, 2025
    Expanding Biomarker Characterization in Deeply Phenotyped DLB, PD and PDD Cohorts
  • Parkinson’s Disease Therapeutics Pipeline Program, 2025
    ACT-02 as a Disease-modifying Therapy for Parkinson’s

    Study Rationale: Parkinson’s disease (PD) is a complex neurodegenerative disorder marked by the loss of dopaminergic neurons, however the underlying exact reasons are still not fully understood...

  • Biomarkers to Support Therapeutic Trials Program, 2025
    Ultra-sensitive Quantification of Phosphorylated LRRK2 in Biofluids from Clinical Trials of Therapeutic Candidates

    Study Rationale: LRRK2 is a protein for which inappropriate activation is associated with Parkinson’s disease (PD). Investigators are therefore pursuing the activity of LRRK2 as a potential...

  • Research Grant, 2025
    Developing an ELISA Immunoassay for Monitoring Phosphorylation of Proteins Associated with Parkinson’s Disease

    Study Rationale: As Parkinson’s disease (PD) progresses, one of the molecular changes that occurs is an increase in the number of phosphate groups that are added to proteins. In this project, we will...

  • Research Grant, 2025
    Assessment of Artificial Intelligence (AI) and Blood-Brain Barrier Technology

    Study Rationale: Companies are currently using artificial intelligence (AI) to design and develop new drugs and developing new ways to get drugs across the protective blood-brain barrier (BBB) and...

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