The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
Search or browse funded studies
Previously funded studies appear chronologically, with the most recent appearing first.
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Improved Biomarkers and Clinical Outcome Measures, 2019Development of a Colony Stimulating Factor 1 Receptor (CSF1R) Radioligand for Imaging Microglia-selective Inflammation
Study Rationale:
We have shown that Parkinson’s disease has an underlying neuroinflammatory component that involves microglia, which are inflammatory and immune cells in the brain. We have developed... -
Improved Biomarkers and Clinical Outcome Measures, 2019Multimodal MR Imaging of the Midbrain for Early Parkinson’s Progression
Study Rationale:
Parkinson’s disease (PD) is marked by the loss of dopamine neurons in part of the midbrain, a section toward the base of the brain that serves important functions in movement. In the... -
Therapeutic Pipeline Program, 2019Miro1-targeting Drug Discovery for Parkinson's Disease
Study Rationale:
There is mounting evidence for involvement of mitochondrial biology in the pathogenesis of Parkinson’s disease (PD). Alterations in mitochondrial dynamics and distribution have been... -
Therapeutic Pipeline Program, 2019Screening for Precision Parkin Activators
Study Rationale:
Defects in the protein parkin cause the loss of nerve cells in the brain and are responsible for many cases of young-onset Parkinson's disease that develops before 50 years of age. We... -
Research Grant, 2018Examining GCase Activity in People with REM Sleep Behavior Disorder
Study Rationale:
Approximately 80 percent of people with REM sleep behavior disorder (RBD) will develop a neurological disorder such as Parkinson's disease (PD). GBA mutations are the most frequent... -
Research Grant, 2019Discovery and Development of Parkin Activators as Therapies for Parkinson’s Disease
Study Rationale:
Impaired mitochondria are a shared feature of Parkinson's disease (PD). Thus restoration of mitochondrial function offers a therapeutic avenue to slow the progression of PD. Parkin...
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Our funding programs support basic, translational and clinical research from academia and industry.