The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
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Previously funded studies appear chronologically, with the most recent appearing first.
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Target Advancement Program, 2021Sex-based Modulation of Neuromelanin-linked Parkinson’s Disease Pathology
Study Rationale:
Parkinson’s disease (PD) is more common in men than in women, and men with PD exhibit earlier onset, faster progression, more severe motor symptoms and more frequent cognitive decline... -
Research Grant, 2021Developing a Diagnostic Test to Detect the Signature Scent of Parkinson’s Disease
Study Rationale:
People with Parkinson’s disease (PD) emit a novel odor that can be detected months to years before the onset of symptoms. The molecules responsible for this characteristic scent are... -
PIPETTE 4R Tau and Alpha-Synuclein PET Tracer Development, 2021Development of Selective Markers for Imaging Abnormal Protein Aggregates in Parkinson’s Disease
Study Rationale:
In neurological disorders such as Parkinson’s disease (PD) or frontotemporal dementia, the proteins alpha-synuclein or tau are structurally altered and accumulate in clumps in the... -
PIPETTE 4R Tau and Alpha-Synuclein PET Tracer Development, 2021Development of a New Class of PET Tracers for Imaging Tau and Alpha-synuclein
Study Rationale:
Parkinson’s disease (PD), Alzheimer’s disease and progressive supranuclear palsy are all characterized by the presence of abnormal aggregations of two proteins in the brain: alpha... -
Target Advancement Program, 2021Pre-clinical Validation of a Novel Target for Dyskinesia Induced by Levodopa
Study Rationale:
The motor symptoms associated with Parkinson’s disease (PD) are treated by replacing dopamine, the brain chemical that is lost when dopamine-producing neurons die. Initially... -
Target Advancement Program, 2021Targeting the Chemical Modification of DNA to Suppress Neurodegeneration in Parkinson’s Disease
Study Rationale:
Genes can be switched on or off by proteins that add and remove chemical modifications to DNA. We and others have shown that the chemical modification of genes important for...
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Our funding programs support basic, translational and clinical research from academia and industry.