The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
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Previously funded studies appear chronologically, with the most recent appearing first.
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Parkinson’s Disease Therapeutics Pipeline Program, 2025IND-enabling Studies of a Promising USP30 Inhibitor as Disease-modifying Therapy for Parkinson's Disease
Study Rationale: While the cause of Parkinson's disease (PD) remains unknown for most patients, strong evidence indicates that damaged mitochondria in neurons likely play a causal role. Mitochondria...
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Research Grant, 2025Clinical Development of the PET Tracer Candidate MODAG-009 for quantitative Detection of Alpha-synuclein Pathology in Parkinson’s Disease
Study Rationale: In both Parkinson's disease and multiple system atrophy (MSA), the protein alpha-synuclein becomes altered, resulting in the accumulation of clumps of aggregated alpha-synuclein in...
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Research Grant, 2024SUPPLEMENT: MJFF Consortium on PRKN and PINK1
Study Rationale: Recessively inherited forms of Parkinson’s disease (PD) caused by mutations on both copies of the genes PRKN and PINK1 are unique in many aspects. Age at onset is mainly before the...
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Research Grant, 2024Virtual Screening and Biochemical Confirmation of Small Molecule Activators of ATP10B
Study Rationale: Disruption of lysosomal glucosylceramide (GluCer) homeostasis is a key risk factor in Parkinson’s disease. ATP10B, a lysosomal GluCer exporter, has been linked to Parkinson’s through...
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Therapeutic Pipeline Program, 2024Integrin CLOAKs as Novel Oral Therapeutics for Parkinson’s Disease
Study Rationale: Increased neuroinflammation promotes neuron injury and loss (neurodegeneration) and drives progression of Parkinson’s Disease (PD), suggesting that controlling neuroinflammation is an...
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Summer 2025 RFP: Accelerating Biological Understanding and Translational Approaches for PD Program - Biomarkers, 2025EV-PREDICT: Identifying Early Biomarkers for Parkinson’s Disease in Blood-derived Neuronal Vesicles
Study Rationale: Parkinson’s disease (PD) is a common and growing brain disorder that currently has no cure and is difficult to diagnose early. A key feature of PD is the abnormal buildup of a protein...
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Our funding programs support basic, translational and clinical research from academia and industry.