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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • MJFF Research Grant, 2011
    Generation of Monoclonal and Polyclonal Antibodies against LRRK1

    Objective/Rationale:
    There is great excitement that drugs targeting an enzyme called LRRK2 may have utility in the treatment of Parkinson’s disease. Some companies are attempting to develop LRRK2...

  • MJFF Research Grant, 2011
    Generation of Monoclonal and Polyclonal Antibodies Against Aggregated Forms of Alpha-Synuclein

    Objective/Rationale:
    The aggregation of alpha-synuclein plays a pivotal role in the development of Parkinson’s disease. This subproject focuses on supporting the MJFF initiative of generating...

  • MJFF Research Grant, 2011
    Implementation of PD GWAS meta-analysis results on the PDGene database

    Objective/Rationale:
    The goal of this proposal is to analyze all available Parkinson’s disease (PD) genomewide association study (GWAS) datasets so that we can identify gene variants associated with...

  • MJFF Research Grant, 2011
    Axonopathy induced by overexpression of human -synuclein in the rat nigrostriatal dopamine system

    Objective/Rationale:
    Observations made in brains from patients with Parkinson’s disease indicate that the disease may start at the level of the axons and that loss of the affected neurons occur later...

  • Rapid Response Innovation Awards, 2011
    Blood-Brain Barrier Modification Using Heterotopic Nasal Mucosal Grafting for Enhanced Symptoms & Side Effects and Macromolecular Disease Modifying Drug Delivery in Parkinson's Disease

    Objective/Rationale:
    One of the most significant problems in the treatment of Parkinson’s disease is the inability to provide continuous and high molecular weight drug delivery to the central nervous...

  • LEAPS, 2011
    Supplement to 'Discovery of mGluR4 Potentiators for Symptoms & Side Effects and Disease-Modifying Treatment of PD'

    Promising Outcomes of Original Grant:
    Activation or potentiation of metabotropic glutamate receptor 4 (mGluR4) is a promising new strategy for both Symptoms & Side Effects and disease-modifying...

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Our funding programs support basic, translational and clinical research from academia and industry.

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