The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
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Previously funded studies appear chronologically, with the most recent appearing first.
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Research Grant, 2020Cytokine Production by Adaptive Immune Cells in Parkinson’s Disease: Response to Diverse Biological Stimuli
Study Rationale:
Many studies indicate a role for the adaptive immune system in Parkinson’s disease. Our study will produce proteins called cytokines that play a role in the immune response to... -
Research Grant, 2020Targeted and Untargeted Mass Spectrometry-Based Proteome Investigation of Urine in Parkinson’s Disease
Study Rationale:
There is an urgent need for disease indicators — also known as biomarkers — in Parkinson’s disease to enable early diagnoses and treatment response monitoring. Urine is a promising... -
Therapeutic Pipeline Program, 2020Photoreceptor-Directed Light Therapy in Parkinson’s Disease
Study Rationale:
Non-motor symptoms including sleep disturbances are common and enormously impact quality of life in people with Parkinson’s disease (PD). Sleep disruption affects motor function... -
Research Grant, 2020Investigating the Role of LRRK2 in Tau Pathogenesis
Study Rationale:
While most cases of Parkinson’s disease have no known genetic cause, a subset of Parkinson’s is caused by mutations in the leucine-rich repeat kinase 2 (LRRK2) gene. It is believed... -
Biosample Use Program, 2020Relationship of Plasma Vitamin B12 and Homocysteine Levels with Outcomes in SURE-PD and STEADY-PD Trials
Study Rationale:
Vitamin B12 levels are lower in people with Parkinson’s disease. Our prior investigation showed that lower B12 levels were associated with more rapid worsening of gait and stability... -
Biosample Use Program, 2020Metabolomic Analysis of Penetrance, Prognosis and Tracking Biomarkers of LRRK2 PD
Study Rationale:
Mutations in a gene called LRRK2 can cause Parkinson's disease but only a quarter to half of the people who carry one of these mutations will actually develop Parkinson’s in their...
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Our funding programs support basic, translational and clinical research from academia and industry.