The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
Search or browse funded studies
Previously funded studies appear chronologically, with the most recent appearing first.
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MJFF Research Grant, 2011Identification of a Novel Calcium Selective Antagonist for Neuroprotection in PD
Objective/Rationale:
Nothing is known to slow or stop the progression of Parkinson’s disease. Our work and that of others suggests that antagonism of calcium channels having a Cav1.3 pore forming... -
LRRK2, 201114-3-3s as Regulators of LRRK2 Toxicity
Objective/Rationale:
This project will evaluate the functional consequences of the interaction between 14-3-3 proteins and LRRK2. 14-3-3 proteins play a crucial role in inhibiting cell death pathways... -
Biomarkers, 2011Salivary Biomarkers for Parkinson's Disease
Objective/Rationale:
Biomarkers are needed for assisting with the diagnosis of Parkinson’s disease (PD) and for monitoring its progression. To date, the most consistent observations pertain to... -
MJFF Research Grant, 2011Analysis of the ENS Using Routine Colonic Biopsies as a Biomarker for PD: Optimizing Detection of Alpha-Synuclein Pathology and Assessment in LRRK2 Patients
Promising Outcomes of Original Grant:
In our original research funded by MJFF, we have shown that the enteric nervous system was readily analyzed using routine colonic biopsies obtained in the course... -
LRRK2, 2011New Roles for the Parkinson's Disease Kinase LRRK2 in Cytoskeletal Dynamics
Objective/Rationale:
LRRK2, a key protein in Parkinson’s disease, may have a role in regulating the cytoskeleton. The cytoskeleton in nerve cells (neurons) is crucial for the growth of neuronal... -
Rapid Response Innovation Awards, 2011Informing Clinical Decision Making in the Pre-motor Period of Parkinson Disease
Objective/Rationale:
Currently, the diagnosis of Parkinson disease (PD) relies on recognition of impaired movement, which occurs decades after neurodegeneration begins. By looking at changes in sleep...
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Our funding programs support basic, translational and clinical research from academia and industry.