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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • LRRK2 in the Immune System, 2012
    LRRK2 Regulates Host Response to Microbial Infections

    Objective/Rationale:             
    We recently formed a research team that comprises Parkinson’s scientists, immunologists, Crohn’s disease experts, virologists and pathologists; this, to explore a...

  • MJFF Research Grant, 2012
    Establishing LRRK2 Signaling Pathways

    Objective/Rationale:             
    Inherited mutations that cause Parkinson’s disease have been studied with earnest since their discovery beginning in the 1990’s.  These genetic alterations point us...

  • MJFF Research Grant, 2012
    Evaluation of PD-linked Transcripts in PPMI

    Objective/Rationale:             
    Confirm associations between the expression of three susceptibility genes and Parkinson’s in peripheral blood of individuals with early-stage, untreated disease, and...

  • MJFF Research Grant, 2012
    In Vivo Characterization of Helper-dependent Adenoviral Vectors Expressing Human LRRK2

    Objective/Rationale:             
    Mutations in the LRRK2 gene are a common cause of familial Parkinson’s disease. Familial LRRK2 mutations induce neuronal toxicity in vitro. Reliable pre-clinical...

  • Research Grant, 2013
    Search for Specific Retinal Biomarkers of Parkinson’s Disease

    Objective/Rationale:       
    Although not usually thought of as part of Parkinson’s disease (PD), relatively subtle changes in vision and retinal structure have been reported among PD patients by...

  • Rapid Response Innovation Awards, 2013
    Epigenetics of Parkinson’s Disease in Japanese Males in the Kuakini Honolulu Heart Program

    Objective/Rationale:
    The goals of the project are to identify a unique set of DNA modifications (methylation) in brain sections of those with and without Parkinson’s disease (PD), exposed to...

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