The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
Search or browse funded studies
Previously funded studies appear chronologically, with the most recent appearing first.
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Research Grant, 2025Fostering Knowledge of Gait in PD Through a Multifaceted Dissemination Approach
Study Rationale: Gait abnormalities are among the most debilitating symptoms of PD, associated with falls, reduced mobility and increased dependency. However, education on gait in PD and developments...
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Accelerating Biological Understanding and Therapeutic Translation for PD- Biology, 2025Role of TFEB Pathway Activators and ISR Inhibitors on Alpha-synuclein Associated Impaired Mitophagy in the a Pre-clinical Model Brain
Study Rationale: Accumulation of faulty mitochondria (the energy generators of our cells) is thought a be a cause of Parkinson’s disease. Therefore, if we could enhance removal and recycling of these...
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Accelerating Biological Understanding and Therapeutic Translation for PD- Biology, 2025Investigating the Interplay Between Mitochondrial DNA-containing VDIMs (vesicles derived from inner mitochondrial membrane) and LRRK2-dependent Lysosomal Defects in Parkinson’s Disease
Study Rationale: Mitochondria-the powerhouses of the cell, contain their own DNA (mtDNA), which when damaged, can cause defects in mitochondrial function. Mitochondria can package mtDNA by into small...
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Accelerating Biological Understanding and Therapeutic Translation for PD-Biomarkers, 2025An International Working Group for the Evaluation of Mitochondrial DNA as a PD Biomarker
Study Rationale: Changes to mitochondria (a compartment of cells important for providing energy) occur in some types of genetic (inherited) PD and PD that arises later in life with no known cause...
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Alpha-Synuclein Post-Translational Modifications Quantification Program, 2025SUPPLEMENT: Spatially Resolved Proteomics for Quantitative Mapping of Post-Translational Modifications of Alpha-synuclein
Study Rationale: Alpha-synuclein is the key protein involved in Parkinson’s disease (PD). In the process of the disease, it loses its proper shape and clumps together. These clumps are toxic to cells...
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Research Grant, 2025SUPPLEMENT: Empowering Community Health Workers in Clinical Research: A Proposal to Enhance the MJFF Clinical Research Training Modules with Multimedia for Greater Impact
The NYU Clinical and Translational Science Institute (CTSI), in collaboration with The Michael J. Fox Foundation, is developing an online, asynchronous, module-based community health worker (CHW)...
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Our funding programs support basic, translational and clinical research from academia and industry.