The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
Search or browse funded studies
Previously funded studies appear chronologically, with the most recent appearing first.
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GBA Biology and Therapies, 2018Structural Characterization of the GCase/LIMP-2 Complex
Study Rationale:
Mutations in the GBA gene are a risk factor for Parkinson’s disease (PD) and cause deficits in the protein GCase. GCase reaches its final destination in the cell, the lysosome, via its... -
Research Grant, 2018Safety and Tolerability of GRF6021 Infusions in People with Parkinson's Disease and Cognitive Impairment
Study Rationale & Design:
Components of blood have been found to improve health and enhance multiple biological functions, including brain function, in older animals. Blood plasma has been... -
Research Grant, 2018The Effect of Psychological Stress on the Symptoms of Parkinson's Disease
Study Rationale:
Many people with Parkinson's disease (PD) experience chronic stress and associated disorders, such as depression, anxiety or both. Furthermore, many people with PD notice worsening of... -
Research Grant, 2018Studying Measures of LRRK2 Activation and Lysosomal Dysfunction in Parkinson's Disease
Study Rationale:
As new, targeted therapies for Parkinson's disease (PD) enter clinical trials, biomarkers -- objective measures of disease --become increasingly important as tools for matching people... -
Research Grant, 2018Developing New Drugs that Deactivate Deubiquitinase Proteins for the Treatment of Parkinson's Disease
Promising Outcomes of Original Grant:
In our past studies, we aimed to identify small molecule inhibitors of proteins called deubiquitinases (DUBs), i.e., chemicals that makes DUBs unable to perform... -
Improved Biomarkers and Clinical Outcome Measures, 2018Expansion of Studies to Develop Tear Biomarkers of Parkinson's Disease
Promising Outcomes of Original Grant:
We previously explored the hypothesis that changes in tear protein content could represent a biomarker -- objective measure -- of Parkinson's disease (PD). Among...
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Our funding programs support basic, translational and clinical research from academia and industry.