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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • MJFF Research Grant, 2010
    Physiological and Pathological Implications of the Unique Subcellular Distribution of LRRK2

    Objective/Rationale: 
    Mutations in the LRRK2 gene are now recognized as the most common genetic cause of Parkinson’s disease, responsible for not only several inherited forms of this movement disorder...

  • MJFF Research Grant, 2010
    Parkinson's Disease NeuroEPIC: A Study of Genes and the Environment

    Objective/Rationale: 
    We will take advantage of the large European Prospective Investigation in Cancer (EPIC), a unique resource involving almost 500,000 participants from 10 European countries, with...

  • Novel Approaches to Drug Discovery, 2010
    Optimizing Metalloporphryins for Clinical Development Supplement

    Promising Outcomes of Original Grant:
    The overall goal of this ongoing proposal is to determine if a newly developed series of metalloporphyrins designed to penetrate blood brain barrier shows promise...

  • MJFF Research Grant, 2010
    Technology for Clinicogenetic Studies of LRRK2 G2019S in Tunisia

    Objective/Rationale:
    We seek to create and enhance a secure database, accessible by collaborators with customizable, user-friendly, web-based entry for clinical, genetic and pedigree information. This...

  • MJFF Research Grant, 2010
    The Parkinson's Progression Markers Initiative (PPMI)

    Objective/Rationale:
    Currently there is no definitive diagnostic test for Parkinson’s disease (PD) in a live patient, and no way to track disease progression on a biological level. These gaps have...

  • Rapid Response Innovation Awards, 2010
    Testing Whether Alpha-Synuclein is Modified by 4-hydroxy-2-nonenal in the Human Brain

    Promising Outcomes of Original Grant:
    The major goal of our grant application was to test whether a protein known as alpha-synuclein becomes toxic to dopamine-secreting nerve cells when it is modified...

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Our funding programs support basic, translational and clinical research from academia and industry.

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