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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • Rapid Response Innovation Awards, 2007
    Development and Initial Characterization of an Enzyme-linked Immunosorbent Assay for the Candidate PD Risk Marker ST13

    Objective/Rationale:
    Clinical signs of Parkinson’s disease develop only after the death of around 70 percent of vulnerable dopaminergic neurons. Laboratory tests for PD are not currently available...

  • Rapid Response Innovation Awards, 2007
    Methylphenidate for the Treatment of Gait Impairment in Parkinson's Disease

    Objective/Rationale:
    The objective of this study is to explore the effects of methylphenidate on the gait of patients with Parkinson’s disease who are experiencing shuffling and freezing...

  • Rapid Response Innovation Awards, 2007
    Understanding the Molecular and Functional Changes of CB1/D2/A2A Receptor Complexes in the Hemi-parkinsonian Pre-clinical Model

    Objective/Rationale:
    Future therapies in Parkinson’s disease (PD) may derive from the existence of intramembrane heteromeric receptor complexes containing the dopamine D2 receptor. The ability of...

  • Rapid Response Innovation Awards, 2007
    A Novel Strategy for the Selection and Transplantation of Dopamine-Specified Human Embryonic Stem Cells

    In parkinson’ disease (PD), neurodegeneration is largely confined to one discrete group of nerve cells that produce the chemical dopamine (DA). Since the death of most DA neurons almost always...

  • Specification, Patterning, and Maintenance of Midbrain Dopam, 2004
    Identification of Novel Determinants for Dopamine Neuron Generation in Vivo and in Embryonic Stem Cells

    Understanding how the different cells of the brain are generated during embryonic development is one of the fundamental questions in biology. Recent studies have elucidated several key mechanisms...

  • MJFF Research Grant, 2004
    Simple Blood Tests for Parkinson's Disease Derived from Genome-wide Expression Changes

    In work from their initial grant, Drs. Steven Gullans and Clemens Scherzer at Brigham and Women’s Hospital identified a number of genes that are differentially expressed in blood cells of patients...

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