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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • Spring 2022 RFA: Therapeutic Pipeline Program Pre-Clinical, 2024
    (SUPPLEMENT) Targeting Phosphoinositides for Parkinson’s Disease Therapy

    Study Rationale: Phosphoinositides (PIPs) are a group of lipids that build cell membranes and play critical roles in mechanisms that control cell’s growth, movement, propagation and death. Recent...

  • Accelerating Biological Understanding and Therapeutic Translation for PD-Biology, 2024
    Alterations in DNA Repair Mechanisms in Parkinson’s Disease Neurons and their Correlation with Clinical Variables

    Study Rationale: Preserving the fidelity of genetic information is essential for life. Consequently, all organisms have developed efficient systems for repairing DNA damage. One of the consequences of...

  • Freezing of Gait Program, 2025
    AID-FOG: Artificial Intelligence-driven Freezing of Gait Detection in the Home

    Study Rationale: Freezing of gait (FOG) is a symptom that causes many people with Parkinson’s disease (PD) to suddenly lose their ability to take a step while walking, creating a high risk for falling...

  • Neuronal Synuclein Disease Endotypes 2024, 2025
    Assessing the Aggregation of Alpha-synuclein Across Aging, Alzheimer’s Disease and Dementia with Lewy Bodies

    Study Rationale: Forms of alpha-synuclein, the protein that aggregates in Parkinson’s disease (PD), can be detected in cerebrospinal fluid (CSF) by seed amplification assays (SAA). These highly...

  • Neuronal Synuclein Disease Endotypes 2024, 2025
    Testing Biofluid Samples from the Arizona Study of Aging and Neurodegenerative Disorders for Alpha-synuclein and Biomarkers of Alzheimer’s Disease

    Study Rationale: The Arizona Study of Aging and Neurodegenerative Disorders (AZSAND) has amassed a comprehensive collection of samples and longitudinal clinicopathological data. In this project, we...

  • Research Grant, 2025
    Evaluation of Novel PET Probes for Alpha-synuclein Imaging

    Study Rationale: Aggregation of the protein alpha-synuclein into fibrils in Lewy bodies and Lewy neurites is the key pathological feature of Parkinson's disease (PD) and related synucleinopathies...

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