The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
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Previously funded studies appear chronologically, with the most recent appearing first.
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Rapid Response Innovation Awards, 2013Regulation of Tau Protein by MicroRNA
Objective/Rationale:
We propose studies to address the overall hypothesis that small ribonucleic acids (RNAs) – molecules that code and regulate genes –contribute to the type of tau protein... -
Research Grant, 2013Identification of RNAs in Carrier Protein and Exosomes Compared to RNA Found in the Whole Sample
Objective/Rationale:
Isolation of RNA biomarkers from biofluids is a new promising approach to monitor health and disease. RNAs exist in different fractions of cell-free biofluids. Some are... -
Research Grant, 2013Inhaled Levodopa as a Treatment for Intermittent Motor Fluctuations in Parkinson’s Disease
Promising Outcomes of Original Grant:
Intrapulmonary delivery of levodopa results in rapid, consistent and predictable augmentation of plasma levodopa levels in both healthy volunteers and subjects... -
Rapid Response Innovation Awards, 2013Neuroprotectin D1 (NPD1) as a Disease-modifying Therapy for Parkinson’s Disease
Objective/Rationale:
Progressive loss of dopaminergic neurons in Parkinson’s disease (PD) involves several pathogenic mechanisms. It may be assumed that drugs acting on more than one... -
Neurotrophic Factors Challenge, 2012Novel Cell-based Strategy for GDNF Delivery in Parkinson's Disease
Objective/Rationale:
Glial cell line-derived neurotrophic factor (GDNF) is the most potent nerve cell growth molecule capable of protecting the dopamine neurons that are affected in... -
LRRK2 in the Immune System, 2012Investigation of Neuroinflammation in LRRK2 Mutation Carriers Using Positron Emission Tomography
Objective/Rationale:
There is evidence that LRRK2 mutation may alter the immune response in such as way as to potentiate neuroinflammatory responses to external triggers, with a...
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Our funding programs support basic, translational and clinical research from academia and industry.