The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
Search or browse funded studies
Previously funded studies appear chronologically, with the most recent appearing first.
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Dyskinesia, 2011Role of Gad1 in l-DOPA-induced dyskinesias
Objective/Rationale:
Levodopa remains the most efficient agent used for the Symptoms & Side Effects treatment of Parkinson’s disease. Unfortunately, levodopa administration for several years also... -
MJFF Research Grant, 2011Estimating Neuroprotective Effects of Nigral AAV-NRTN Using Selective Reaction Monitoring to Quantitatively Measure p-erk1/2 Signaling Strength in Nigral DA Neurons
Objective/Rationale:
Pre-clinical studies indicate that neurotrophic factor gene therapy has the potential to attenuate, delay and perhaps prevent the progressive loss of nigral DA neurons in aging... -
Dyskinesia, 2011Development of a Treatment for Dyskinesia Targeting Opioid Receptors
Objective/Rationale:
Levodopa-induced dyskinesias (LID) affect the majority of patients with advanced Parkinson’s disease, compounding their disability. Therefore, drugs that prevent or limit LID are... -
Rapid Response Innovation Awards, 2011Novel Neuroprotective Cell-Penetrating Peptides
Objective/Rationale:
Mesencephalic Astrocyte-derived Neurotrophic Factor (MANF) is currently one of the most potent factors protecting and rescuing neurons in pre-clinical models of Parkinson’s... -
Research Grant, 2011Comparing Cognitive Scales in the MUSTARDD-PD Study
Objective/Rationale:
Some people with Parkinson’s may develop dementia during their disease course. Being able to detect problems with mental function at an early stage, to monitor and to reliably... -
Rapid Response Innovation Awards, 2011Testing Novel Compounds for Noninvasive Delivery of Small Interfering RNA into CNS
Objective/Rationale:
Small interfering RNA (siRNA) molecules have been successfully used to target specific genes in cell culture. However, the lack of specificity for siRNA to cells and lack of...
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Our funding programs support basic, translational and clinical research from academia and industry.