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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • Accelerating Biological Understanding and Therapeutic Translation for Parkinson’s Disease Program, 2023
    Analysis of the Lysosomal Lipid Metabolism Pathway and Other Pathways, Subgroups and Stages in Parkinson’s Disease

    Study Rationale: Lysosomes are cellular compartments involved in clearing molecular debris. Several genes that work in the lysosome, including GBA1, GALC, SMPD1 and others, are known to be involved in...

  • 2022: Accelerated Therapeutics Program, 2024
    (SUPPLEMENT) Small Molecule Mitochondrial Modulators for the Treatment of Parkinson's Disease

    Study Rationale: Mitochondrial dysfunction is a crucial driver of the initiation and progression of Parkinson’s disease (PD). Mitochondria are structures that produce cellular energy, and in neurons...

  • Research Grant, 2023
    Construction of a Library of Digital Technologies for Use in Research and Care of Parkinson’s Disease

    Study Rationale: The past decade has seen enormous growth in commercially available digital technologies — including sensors, devices and smartphone apps — for the detection and monitoring of...

  • Research Grant, 2024
    Powered Clothing and Wearable Robotics for Everyday Gait Support

    Study Rationale: We’ve spent several years exploring the potential of supporting human movement with wearable robotics and we believe our work has tremendous potential for individuals with Parkinson’s...

  • Research Grant, 2023
    Chronos-PD: Using Proteomic Analysis to Detect Early Molecular Signatures of Parkinson’s Disease

    Study Rationale: Parkinson’s disease (PD) is a gradually progressive condition: by the time the disorder is recognized and diagnosed, it is often too late to protect or reverse the damage that has...

  • Accelerating Biological Understanding and Therapeutic Translation for Parkinson’s Disease Program, 2023
    Analysis of Skin Biopsies from the Systemic Synuclein Sampling Study by Alpha-synuclein Seed Amplification Assay

    Study Rationale: Alpha-synuclein seed amplification assays have been shown to enable an accurate and early diagnosis of Parkinson’s disease (PD). However, this test currently relies on cerebrospinal...

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