The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
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Previously funded studies appear chronologically, with the most recent appearing first.
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Parkinson’s Disease Therapeutics Pipeline Program, 2024Development of a First-in-class Inhibitor of the “Mitochondrial Permeability Transition Pore” as a Novel Disease-modifying Treatment for Parkinson’s Disease
Study Rationale: Mitochondria are subcellular structures that produce energy and help regulate the movement of calcium ions that continually flow into brain cells when they are active, ions that can...
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Research Grant, 2024Measurement of Phosphorylated Alpha-synuclein in Skin Biopsies as a Prospective Biomarker for Parkinson’s Disease
Study Rationale: Parkinson’s disease (PD) is associated with an accumulation of phosphorylated alpha-synuclein, and the amount of the protein increases as PD progresses. We have found that we can...
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Research Grant, 2024Assessment of Longitudinal Imaging Using Radiolabeled AV-133 in Early and Prodromal Parkinson’s Disease
Study Rationale: The clinical phase of Parkinson’s disease (PD) is preceded by a prodromal phase of progressing neurodegeneration that can last many years. Imaging markers such as radiolabeled AV-133...
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Research Grant, 2024Developing Community Health Worker Remote Training Modules on Research, Brain Health and Parkinson’s Disease
Study Rationale: Neurodegenerative diseases including Parkinson's disease (PD) disproportionately impact underserved communities due to barriers in research participation and awareness. Community...
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Freezing of Gait, 2024Use of Soft Robotic Apparel to Prevent Freezing of Gait in Parkinson’s Disease
Study Rationale: Freezing of gait (FoG) is a disabling walking problem that leads to loss of mobility, falling and poor quality of life in many people with Parkinson’s disease (PD). People with FoG...
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Parkinson’s Disease Therapeutics Pipeline Program, 2024Development of Selective Ion Channel Inhibitors as a Disease-modifying Therapy for Parkinson’s Disease
Study Rationale: Our aim is to develop an oral medication that will protect the dopamine neurons whose loss is thought to be the cause Parkinson’s disease (PD). Evidence suggests that excessive levels...
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Our funding programs support basic, translational and clinical research from academia and industry.