The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
Search or browse funded studies
Previously funded studies appear chronologically, with the most recent appearing first.
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Target Validation, 2014Transferrin Receptor 2 as a Target to Halt Iron Overload in Parkinson's Disease
Objective/Rationale:
Iron is an element naturally present in the brain and is required for its proper function. Iron levels, however, must be tightly controlled because excessive amounts... -
Research Grant, 2014Phase IIb Study of Intranasal Glutathione in Parkinson’s Disease
Study Rationale:
The loss of the antioxidant glutathione in the brain of individuals with Parkinson’s disease (PD) occurs years before the onset of motor symptoms. Glutathione has... -
Target Validation, 2014Inhibition of a Dopamine Receptor in Lymphocytes as a Treatment for Parkinson's Disease
Objective/Rationale:
Emerging evidence has shown that lymphocytes, a kind of immune system cells, play a fundamental role in the development and progression of Parkinson's diseases. Our... -
Research Grant, 2014Accelerated Pre-clinical Development of a Novel and Specific Alpha-synuclein Tracer
Objective/Rationale:
Biomarkers that can communicate the underlying pathology of Parkinson’s disease (PD) in living patients would be invaluable for diagnosis and for evaluation of disease-modifying... -
Cognition Biomarkers, 2014miRNA Markers of Cognition
Objective/Rationale:
In previous MJFF-funded research, these researchers identified four promising microRNAs (which regulate gene expression) associated with cognitive status. They profiled the miRNAs... -
Parkin Biology, 2014Role of Parkin in Innate Immunity
Objective/Rationale:
The protein Parkin contributes to the elimination of damaged mitochondria by a process called mitophagy. Prior research has shown that silencing Parkin gene affects innate immunity...
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Our funding programs support basic, translational and clinical research from academia and industry.