The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
Search or browse funded studies
Previously funded studies appear chronologically, with the most recent appearing first.
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Clinical Intervention Awards, 2013Dipraglurant for Levodopa-Induced Dyskinesia Pre-phase IIB Studies
Study Rationale:
Dipraglurant is a modulator of the metabotropic glutamate receptor 5 (mGluR5). Blockade of this receptor has been shown to have anti-parkinsonian and anti-dyskinetic... -
Neurotrophic Factors Challenge, 2013Exploring a Novel Neurotrophic Factor to Protect the Nigrostriatal Dopaminergic System and Alleviate Motor Deficits
Objective/Rationale:
Safety and effectiveness in brain delivery remain two major challenges in developing novel neuroprotective agents to treat Parkinson’s disease (PD) patients. This... -
Cognition Biomarkers, 2013Insulin-like Growth Factor-1 and DAT Imaging as Biomarkers of Early Cognitive Impairment in Parkinson’s Disease
Objective/Rationale:
Evidence supports that the protein insulin-like growth factor-1 (IGF-1) may be involved in cognitive deficits. An earlier study found that low serum IGF-1 levels... -
Rapid Response Innovation Awards, 2013Novel Quantification Paradigm in Parkinson’s Disease Neurochemical Imaging
Objective/Rationale:
Parkinson’s disease imaging using dopamine transporter (DAT) single-photon emission computed tomography (SPECT) technology conveys important information on brain... -
Rapid Response Innovation Awards, 2013Novel Method for Therapeutic Gene Silencing in the Brain
Objective/Rationale:
Reducing the activity of certain genes — called gene silencing — implicated in Parkinson’s disease may be a therapeutic approach that could prevent or slow the disease... -
Access to Data and Biospecimens, 2013Alpha-Galactosidase A and Glycosphingolipid Metabolites as Putative Biomarkers for Parkinson’s Disease
Objective/Rationale:
Alpha Galactosidase A (alpha-Gal A) is an enzyme that is ordinarily responsible for lipid recycling in cells. Researchers have shown how pre-clinical models that lack...
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Our funding programs support basic, translational and clinical research from academia and industry.