The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
Search or browse funded studies
Previously funded studies appear chronologically, with the most recent appearing first.
-
Rapid Response Innovation Awards, 2012Role of Brain-specific PGC-1Alpha Isoforms in Parkinson's Disease
Objective/Rationale:
Impaired mitochondrial function and enhanced oxidative stress play a major role in the pathogenesis of Parkinson’s disease (PD). PGC-1alpha is a transcriptional... -
LRRK2 in the Immune System, 2012LRRK2 Regulates Host Response to Microbial Infections
Objective/Rationale:
We recently formed a research team that comprises Parkinson’s scientists, immunologists, Crohn’s disease experts, virologists and pathologists; this, to explore a... -
MJFF Research Grant, 2012Establishing LRRK2 Signaling Pathways
Objective/Rationale:
Inherited mutations that cause Parkinson’s disease have been studied with earnest since their discovery beginning in the 1990’s. These genetic alterations point us... -
MJFF Research Grant, 2012Evaluation of PD-linked Transcripts in PPMI
Objective/Rationale:
Confirm associations between the expression of three susceptibility genes and Parkinson’s in peripheral blood of individuals with early-stage, untreated disease, and... -
MJFF Research Grant, 2012In Vivo Characterization of Helper-dependent Adenoviral Vectors Expressing Human LRRK2
Objective/Rationale:
Mutations in the LRRK2 gene are a common cause of familial Parkinson’s disease. Familial LRRK2 mutations induce neuronal toxicity in vitro. Reliable pre-clinical... -
Neurotrophic Factors Challenge, 2012Novel Cell-based Strategy for GDNF Delivery in Parkinson's Disease
Objective/Rationale:
Glial cell line-derived neurotrophic factor (GDNF) is the most potent nerve cell growth molecule capable of protecting the dopamine neurons that are affected in...
Apply for a Grant
Our funding programs support basic, translational and clinical research from academia and industry.