The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
Search or browse funded studies
Previously funded studies appear chronologically, with the most recent appearing first.
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Research Grant, 2011LRRK2 Antibody Comparison 2011
Objective/Rationale:
LRRK2 (Leucine-Rich Repeat Kinase 2) is a protein thought to be involved in regulating signaling pathways in cells. Mutations in the gene for LRRK2 are associated with some... -
Target Validation, 2011Role of PARK18 in Parkinson's Disease
Objective/Rationale:
PARK18 is a genetic marker that was recently found to be associated with susceptibility to Parkinson’s disease (PD). The marker is encoded within the HLA-DRA gene, a gene that... -
MJFF Research Grant, 2011fMRI of First Degree Relatives of LRRK2 Positive PD Patients
Objective/Rationale:
First, to study the effect of the presence of the LRRK2 G2019S mutation on brain activation patterns in Parkinson’s disease (PD) patients who recently converted into a diseased...
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Repositioning Drugs for PD, 2011Fasudil as a Novel Therapeutic for the Treatment of Parkinson's Disease
Objective/Rationale:
The therapeutic drug we will repurpose for Parkinson’s disease (PD) is fasudil, a kinase inhibitor with an impressive safety profile in humans. The target of fasudil is highly... -
Repositioning Drugs for PD, 2011DPP-4 Inhibitors for the Treatment of Parkinson's Disease
Objective/Rationale:
This is a collaborative research project between three organizations, NIDA, NIA and Pfizer, focused towards characterizing whether gliptins, a well-tolerated drug class effective... -
Repositioning Drugs for PD, 2011Repositioning BCG Vaccination as an Immunostimulant for Slowing the Progression of PD
Objective/Rationale:
We recently demonstrated that strong immune system stimulation created by treating pre-clinical models with a safe vaccine (called BCG) can have a restorative effect on...
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Our funding programs support basic, translational and clinical research from academia and industry.