The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
Search or browse funded studies
Previously funded studies appear chronologically, with the most recent appearing first.
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Community Fast Track, 2007The Protein Engrailed as a Potential Therapeutic Target in Parkinson's Disease
Promising Outcomes of Original Grant:
In our original grant, we have confirmed that a protein called Engrailed (which plays an important role both in the developping and in the adult dopaminergic... -
Community Fast Track, 2007CDNF - A Novel Conserved Neurotrophic Factor that Protects Midbrain Dopaminergic Neurons in vivo
Promising Outcomes of Original Grant:
Future treatment of Parkinson’s disease aim at therapies which would stop the progress of the disease and restore the function of injured dopamine nerves in the... -
Target Validation, 2007Targeting Urate: A Molecular Correlate of Both Risk and Progression in PD
Objective/Rationale:
Urate (a natural antioxidant, caffeine analog and DNA metabolite) is the first molecule linked to both the risk of typical Parkinson’s disease and its rate of progression. Higher... -
Rapid Response Innovation Awards, 2007Potential Utility of Novel CNS-active Experimental Therapeutics for Parkinson's Disease
Objective/Rationale:
Evidence suggests that overproduction of inflammatory molecules, called proinflammatory cytokines, from glial cells in the brain can contribute to nerve cell death and accelerate... -
Rapid Response Innovation Awards, 2007Neuroprotective effects of isradipine in a pre-clinical model of Parkinson’s disease
Objective/Rationale:
Recent work by our group has shown that blocking L-type Ca2+ channels protects vulnerable dopaminergic neurons in three animal models Parkinson’s disease (PD). Isradipine, a high... -
Rapid Response Innovation Awards, 2007Genetic characterization of Omi/Htra2 (PARK13) in autosomal dominant and sporadic Parkinson’s disease
Objective/Rationale:
Identification of DNA variations that cause familial/sporadic parkinsonism has provided insight into the biological pathways involved in disease. Thirteen loci (PARK1-13) have...
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Our funding programs support basic, translational and clinical research from academia and industry.