The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
Search or browse funded studies
Previously funded studies appear chronologically, with the most recent appearing first.
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Expanding Biological Understanding of Parkinson's Disease, 2022Investigation of the Role of PINK1 in Regulating Immune Signaling in Mitochondria
Study Rationale: Evidence is accumulating that the Parkin and PINK1, gene products whose activities are altered in Parkinson’s disease (PD), play a role in immune signaling. We previously identified a...
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Research Grant, 2022Shoring Up a Medical Chemistry Approach to Treating Parkinson’s Disease: The Bridge Initiative
Study Rationale: The proteins parkin and GCase show a strong genetic link to Parkinson’s disease (PD) and are key players of biological pathways often disrupted in the disorder. This connection makes...
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Therapeutic Pipeline Program, 2022Assessing the Effects of USP30 Inhibitors on the Removal of Damaged Mitochondria in Nerve Cells
Study Rationale: Mitochondrial dysfunction is extensively associated with genetic and sporadic forms of Parkinson’s disease (PD). Yet there are currently no clinical trials that specifically aim to...
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Research Grant, 2022Monitoring Prodromal and De Novo Parkinson’s Disease (PRONOVO) Using Multi-modal Imaging
Study Rationale: Individuals with Parkinson’s disease (PD) display variable impairment of the brain and peripheral nervous system, suggesting that PD includes a range of subtypes. Yet the underlying...
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Research Grant, 2022Using Integrated Biomarkers of Prodromal Parkinson’s Disease to Assess the Efficacy of Exercise Intervention in the Earliest Phase of Disease
Study Rationale: In individuals with Parkinson’s disease (PD), the pathological processes are already advanced by the time a clinical diagnosis is made. This delay contributes to the difficulty in...
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Research Grant, 2022LEARN-ATMP – Using the Patient Voice to Develop a Framework for Accessible ATMP Trials
Study Rationale: New therapies for Parkinson’s disease (PD) that involve the use of cells or genes — sometimes called advanced therapy medicinal products (ATMP) — are being developed and tested in...
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Our funding programs support basic, translational and clinical research from academia and industry.