The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
Search or browse funded studies
Previously funded studies appear chronologically, with the most recent appearing first.
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Research Grant, 2017Inflammatory Parkinson's Clinical Biomarker Profiling
Study Rationale:
This study aims to compare the immune system of Parkinson's disease (PD) patients and their caregivers in an effort to determine differences between these groups. Several recently... -
Target Advancement Program, 2018Role of 5-alpha Reductase 1 in the Therapy of Neurodegeneration and Levodopa-induced Dyskinesias
Study Rationale:
The two main types of the enzyme 5α-reductase (5αR) play a key role in the production of steroids in the brain and other organs. In pre-clinical testing, we found that inhibitors of... -
Therapeutic Pipeline Program, 2018Discovery and Development of Novel Parkin Activators
Study Rationale:
Parkinson's disease is characterized by a loss of nerve cells (neurons) in the brain resulting potentially from their inability to remove damaged mitochondria, which control energy... -
Research Grant, 2018Developing Biosignatures of Parkinson's Disease Using Sense of Smell Supplement
Promising Outcomes of Original Grant:
Recent reports of people with “super-smelling powers” have triggered the idea that there exists a specific scent in Parkinson’s patients’ sebum, an oily skin... -
Target Advancement Program, 2018Evaluation of PARIS ASOs in Models of Parkinson's Disease
Study Rationale:
The parkin-interacting substrate (PARIS) prevents genes that are important in the survival of dopamine neurons from working by limiting their expression in neurons. Previously we... -
Therapeutic Pipeline Program, 2018Bitopertin to Alleviate Dyskinesia in Parkinson's Disease
Study Rationale:
Levodopa-induced dyskinesia is abnormal involuntary movements that can affect people with Parkinson's disease after years of treatment. Available therapies for dyskinesia are only...
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Our funding programs support basic, translational and clinical research from academia and industry.