The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
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Previously funded studies appear chronologically, with the most recent appearing first.
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Biosample and Tissue Resource, 2013Measuring LRRK2 Levels and Activity in Sporadic Parkinson’s Disease
Objective/Rationale:
Mutations in the leucine-rich repeat kinase 2 (LRRK2) gene have been linked to Parkinson’s disease (PD). The most prevalent mutation, G2019S, results in increased... -
Parkin Biology, 2013Identification of De-ubiquitinating Enzymes for Parkin-mediated Mitophagy
Objective/Rationale:
There is an urgent need to understand the cell processes that contribute to the cause of Parkinson’s disease. Parkin is an active enzyme within the cell that provides... -
Rapid Response Innovation Awards, 2013“Smart” Gene Therapy for Parkinson’s Disease
Objective/Rationale:
Gene therapies for Parkinson’s disease (PD) aim to produce therapeutic proteins in diseased brain regions to promote neuron survival. Overexpression of these proteins... -
Rapid Response Innovation Awards, 2013Tobacco Mosaic Virus Antibody and Risk of Parkinson’s Disease
Objective/Rationale:
Cigarette smoking is associated with a lower risk of Parkinson’s disease (PD), but its protective mechanism is unknown. Tobacco mosaic virus (TMV), a plant pathogen... -
Dyskinesia Challenge, 2013Oxytocin Effects on Levodopa-induced Dyskinesias
Objective/Rationale:
The objective of this project is to describe the potential antidyskinetic properties of the hormone oxytocin. Oxytocin is found in brain areas that are negatively... -
Research Grant, 2013Deep Sequencing Mass Spectrometry to Identify Biomarkers of Parkinson’s Disease in Cerebrospinal Fluid
Objective/Rationale:
Parkinson’s disease typically goes undetected until clinical diagnosis based on physical manifestations such as rigidity, resting tremor and slowness of movement. Unfortunately...
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Our funding programs support basic, translational and clinical research from academia and industry.