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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • Biomarker Development, 2012
    The Fox Investigation for New Discovery of Biomarkers (BioFIND)

    Objective/Rationale:             
    Biomarkers — a biological marker of disease presence or risk like cholesterol level for heart disease — will greatly aid clinicians’ ability to diagnose Parkinson’s...

  • Target Validation, 2012
    VPS35 as a Novel Target for Parkinson's Disease

    Objective/Rationale:

    Mutations in the VPS35 gene were recently identified as a cause of autosomal dominant familial Parkinson's disease (PD). How mutations in VPS35 precipitate the demise of...

  • Critical Challenges in PD: Postural Instability and Gait Dis, 2012
    Targeted Cognitive Training Program for Freezing of Gait

    Promising Outcomes of Original Grant:
    In our original study we investigated the processes underlying the freezing phenomenon in PD. In this work we found symptoms of freezing of gait (FOG) could be...

  • Rapid Response Innovation Awards, 2012
    Is the Xenomitochondrial Pre-clinical model an ‘Ideal’ Parkinson’s Disease Model?

    Objective/Rationale:
    The lack of a pre-clinical model that exhibits key features of human Parkinson’s disease is an impediment to research progress. In this project we will determine whether a novel...

  • MJFF Research Grant, 2012
    The Role of Alpha-synuclein in the Pathogenesis of Parkinson’s Disease in a Pre-clinical Model

    Objective/Rationale:
    Preliminary data from our laboratory demonstrated that the protein alpha synuclein (a-syn) might play a major role in an inherited autosomal recessive pre-clinical model for...

  • Rapid Response Innovation Awards, 2012
    Polyglutamine Repeats and Parkinson Disease

    Objective/Rationale:             
    Trinucleotide repeat expansion is a gene mutation where the codons (the groups of DNA components that correspond to amino acids) exceed the maximum of a certain gene...

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