The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
Search or browse funded studies
Previously funded studies appear chronologically, with the most recent appearing first.
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Target Validation, 2014Inhibition of a Dopamine Receptor in Lymphocytes as a Treatment for Parkinson's Disease
Objective/Rationale:
Emerging evidence has shown that lymphocytes, a kind of immune system cells, play a fundamental role in the development and progression of Parkinson's diseases. Our... -
Research Grant, 2014CD163+ Macrophages as Tools for Neuroinflammatory Modulation in Parkinson’s Disease Supplement
Promising Outcomes of Original Grant:
Our fundamental hypothesis was that modulation of blood CD163+ macrophages using nanoparticles loaded with anti-inflammatory drugs could protect neurons in the... -
Linked Efforts to Accelerate Parkinson’s Solutions, 2014Alpha-Synuclein Assay Standardization LEAPS
Study Rationale:
The presence of alpha-synuclein protein in biofluids such as blood, cerebrospinal fluid and saliva has been reported by multiple scientists using a variety of analytical techniques... -
Target Validation, 2014Alpha-Galactosidase A as a Therapeutic Target for Parkinson’s Disease
Objective/Rationale:
Alpha Galactosidase A (alpha-Gal A) is an enzyme that recycles lipids in cells. Our preliminary data demonstrates alpha-Gal A deficiency in brains of Parkinson’s... -
Research Grant, 2014Saliva Alpha-synuclein Levels in LRRK2 Mutation Carriers
Study Rationale:
Biomarkers are needed to assist with the diagnosis of Parkinson’s disease (PD) and with monitoring its progression. Decreased levels of alpha-synuclein in cerebrospinal fluid... -
Therapeutic Pipeline Program, 2014Optimization of Dopamine D4 Antagonists for the Treatment of Levodopa-induced Dyskinesia
Study Rationale:
Levodopa-induced dyskinesia is a major dose-limiting effect associated with long-term treatment of Parkinson’s disease (PD). There are no effective treatments for...
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Our funding programs support basic, translational and clinical research from academia and industry.