The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
Search or browse funded studies
Previously funded studies appear chronologically, with the most recent appearing first.
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Access to Data and Biospecimens, 2014Metabolomic Analysis of Parkinsonian Disorders
Study Rationale:
This study is a search for biomarkers of Parkinson’s disease (PD) that would provide early diagnostic clues or a means to monitor disease progression (or both). The analysis involves... -
Rapid Response Innovation Awards, 2014Directed Evolution of Bacteria for Recombinant Expression and Purification of LRRK2
Study Rationale:
Mutations in the gene that encodes the LRRK2 protein are frequent causes of Parkinson’s disease (PD). An obstacle to understanding how these mutations lead to PD is... -
Rapid Response Innovation Awards, 2014Defining the Contribution of Neuroinflammation to Parkinson's Disease
Study Rationale:
Over-activation of brain immune cells, called microglia, is associated with the degeneration that occurs in Parkinson’s disease. This suggests that brain... -
Therapeutic Pipeline Program, 2014Augmenting Treatment Effects of Voice Therapy in Parkinson’s Disease
Study Rationale:
Speech and voice disorders are common in people with Parkinson’s disease (PD) and adversely affect their communication and quality of life. Presently, Lee Silverman... -
Research Grant, 2014Novel Nicotinic Receptor Agonist for Treating Levodopa-induced Dyskinesia
Promising Outcomes of Original Grant:
Our initial hypothesis was two-fold: first, that specific nicotinic (chemical messenger) receptor subtypes are involved in nervous system responses to levodopa and... -
Target Validation, 2013Effects of IL-10 on Neurodegeneration in Mutant Alpha-Synuclein Transgenic Models
Objective/Rationale:
One of the hallmark pathologies in the brains of patients with Parkinson’s disease (PD) is an inflammatory response. We will test whether the cytokine interleukin-10...
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Our funding programs support basic, translational and clinical research from academia and industry.