The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
Search or browse funded studies
Previously funded studies appear chronologically, with the most recent appearing first.
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Research Grant, 2013Advancement of Quantitative Disease Progression Modeling of Parkinson’s Disease
Objective/Rationale:
In clinical trials, the progression of Parkinson’s disease (PD) is primarily measured by the change in total Unified Parkinson Disease Rating Scale (UPDRS) score... -
Rapid Response Innovation Awards, 2012Reversing Pre-existing Pathologies of Dopamine Neurons in an Alpha-synuclein Model
Objective/Rationale:
Alpha-synuclein has been identified to play the central role in Parkinson’s disease. Genome-wide association studies confirm alpha-synuclein as a risk factor for... -
Research Grant, 2013Dynamics of Alpha-synuclein Aggregation in Dopamine Neuron Degeneration and Recovery
Promising Outcomes of Original Grant:
Alpha-synuclein is the central player for Parkinson’s disease. Therapies to decrease levels of alpha-synuclein are promising in curing PD. However, it is unknown... -
Rapid Response Innovation Awards, 2013DNA Methylation as a Biomarker for Parkinson’s Disease
Objective/Rationale:
We will test the hypothesis that whole blood DNA methylation in Parkinson’s disease (PD) will be altered at specific sites compared to either healthy controls or to... -
Rapid Response Innovation Awards, 2013Feeding with Clostridium Leptum for Restoring the Integrity of the Striatal Dopaminergic System in a Pre-clinical Model of Parkinson’s Disease
Objective/Rationale:
Inflammation contributes to the pathogenic process of Parkinson’s disease (PD). Increased numbers of anti-inflammatory regulatory T cells (Tregs) has been associated... -
Synuclein Therapeutic Acceleration Program, 2013Quinpramine for Parkinson’s Disease
Objective/Rationale:
A part of Parkinson’s disease progression involves abnormal aggregation of normal brain proteins into knots of insoluble irritant material. The protein involved in...
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Our funding programs support basic, translational and clinical research from academia and industry.