The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
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Previously funded studies appear chronologically, with the most recent appearing first.
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Rapid Response Innovation Awards, 2013Effect of Alpha-Synuclein Depletion in Dopamine Neurons of Pre-Clinical Models
Objective/Rationale:
A key event in the development of pathological changes in the nervous system of Parkinson’s disease patients is aggregation of a small synaptic protein: alpha-synuclein. Certain... -
Dyskinesia Challenge, 20135-Hydroxytryptophan and Eltoprazine for the Treatment of Levodopa-Induced Dyskinesia
Objective/Rationale:
The appearance of dyskinesia presents new challenges as a symptom of long-term Parkinson’s therapy with levodopa. Our recent studies have identified the serotonin... -
MJFF Research Grant, 2013Angiogenic Biomarkers in PD Dementia: Clinical-Biochemical-Pathological Correlations
Objective/Rationale:
Many patients with Parkinson´s disease (PD) eventually develop dementia, a severe form of cognitive deterioration, and widespread neurodegenerative processes affecting the...
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Rapid Response Innovation Awards, 2013Enteric Glial Cells as a New Source of Biomarkers for PD
Objective/Rationale:
The neural network of the gut called the enteric nervous system (ENS) is affected by the pathological process in PD. One of the relevant features of the ENS is its accessibility... -
Rapid Response Innovation Awards, 2013Protease-Activated Receptor-2 Expression in Parkinson’s Disease
Objective/Rationale:
Inflammation in the brain (neuroinflammation) is an ongoing process in Parkinson's disease and contributes to cell death. Anti-inflammatory compounds are... -
Rapid Response Innovation Awards, 2013The Influence of Bacterial Amyloid on Alpha-synuclein Misfolding in a Pre-clinical Model
Objective/Rationale:
In Parkinson’s disease (PD), in nerve cells in the brain and in the intestine, alpha-synuclein proteins are misformed with abnormal folds and develop small toxic...
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Our funding programs support basic, translational and clinical research from academia and industry.