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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • Research Grant, 2021
    Hidden Sorrows of Covid-19: Impact of Stress on Parkinson’s Disease Progression

    Study Rationale: People living with Parkinson’s disease (PD) are very sensitive to stress, which worsens motor symptoms (such as tremor) and leads to anxiety and depression. Studies in animals suggest...

  • Target Advancement Program, 2021
    Exploring How a Chemical Produced by Intestinal Microbes Contributes to the Pathology and Progression of Parkinson's Disease

    Study Rationale: Imbalances in the bacteria that inhabit the gut have been linked to the onset and progression of Parkinson’s disease (PD). However, the mechanisms by which an altered microbiome can...

  • Expanding Biological Understanding of PD, 2021
    Dissecting the Role of GBA1 and LRRK2 in Regulating the Formation of Lewy Bodies

    Study Rationale: A key hallmark of Parkinson’s disease (PD) is the accumulation of alpha-synuclein aggregates inside neurons. These aggregates are known as Lewy bodies (LBs). Although mutations in...

  • Aligning Science Across Parkinson's, 2021
    Olfactory Circuits: Alpha-Synuclein-Rich Neurons Respond to Environmental Triggers at the Origin of Parkinson’s Disease
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    Study Rationale:
    To slow the progression of Parkinson's disease (PD), we need to know more about how it starts. It is well known now that many individuals with PD have had a significant reduction in...

  • Aligning Science Across Parkinson's, 2021
    Basal Ganglia Networks in Parkinson's Disease
    ASAP logo

    Study Rationale:
    People with Parkinson's disease have long been known to display remarkable motor abilities under special circumstances such as smooth walking with certain visual or auditory cues...

  • Aligning Science Across Parkinson's, 2021
    Distributed Circuit Dysfunction Underlying Motor and Sleep Deficits in a Progressive Model of Parkinson’s Disease
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    Study Rationale:
    Parkinson’s disease (PD) begins decades before it compromises the ability to move about in the world and sleep through the night. Understanding how the dysfunction of brain circuits...

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